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Introduction to Proteomics

Public Education pages
Proteomics Symposium | Public Open House | Proteomics Mini-courses
Proteomics Journal Club | Proteomics Training Program

Introduction to Proteomics (PDF)

Other tutorials available on-line:

• Proteomics Primer
  
• Protein Identification Tutorial 
• Guide to Protein Post-Translational Modifications
  
• De Novo Peptide Sequencing Tutorial
  
• Deamidation in Proteins and Peptides

Proteomics Tools Available on-line:

• Mascot - Peptide mass fingerprint, Sequence query and MS/MS ion search for protein identification from Matrix Science Ltd., London
  
• ProteinProspector – UCSF proteomics tools for fragment-ion masses data (MS-Tag, MS-Seq, MS-Product, etc.)
• ProFound - Search known protein sequences with peptide mass information from Rockefeller University
  
• ProSight PTM: identification and characterization of intact proteins (and their post- translational modifications, PTMs) using the Top-Down Approach.
  
• PeptIdent: a tool that allows the identification of proteins using pI, Mw and peptide mass fingerprinting data. - by ExPASy
  
• PeptideCutter: predicts potential cleavage sites cleaved by proteases or chemicals in a given protein sequence. - by ExPASy
• TagIdent: a tool that allows the identification of proteins by matching a short sequence tag of up to 6 amino acids against proteins in the SWISS-PROT/TrEMBL databases close to a given pI and Mw. - by ExPASy
• FindMod: a tool that can predict potential protein post-translational modifications (PTM) from known PTMs in the database and find potential single amino acid substitutions in peptides. - by ExPASy
  
• GlycoMod: a tool that can predict the possible oligosaccharide structures that occur on proteins from their experimentally determined masses. The program can be used for free or derivatized oligosaccharides and for glycopeptides. - by ExPASy
  
• Compute pI/Mw: for calculation of the theoretical pI (isoelectric point) and Mw (molecular weight) –ExPASy
  
• NCBI BLAST: A tool that allows protein and nucleotide BLAST (Basic Local Alignment Search Tool). - by NCBI
  

Proteomics Journals:

• Molecular & Cellular Proteomics
  
• Proteomics
  
• Journal of Proteome Research

Proteomics Societies:

• HUPO (Human Proteomics Organization)
  
• USHUPO
  
• The Association of Biomolecular Resource Facilities