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Most Recent Publications

171. Melby, J.A.; Brown, K.A.; Gregorich, Z.R.; Roberts, D.S.; Chapman, E.A.; Ehlers, L.E.; Gao, Z.; Larson, E.J.; Jin, Y.; Lopez, J.R.; Hartung, J.; Zhu, Y.; McIlwain, S.J.; Wang, D.; Guo, W.; Diffee, G.M.; Ge, Y. High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms. PNAS. 2023, 120(19), e2222081120. Article
170. Rossler, K.J.; de Lange, W.; Mann, M.W.; Aballo, T.J.; Melby, J.A.; Zhang, J.; Kim, G.; Bayne, E.F.; Zhu, Y.; Farrell, E.T.; Kamp, T.J.; Ralphe, J.C.; Ge, Y. Lactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs. bioRxiv. 2023. Article
169. Rogers, H.T.; Roberts, D.S.; Larson, E.J.; Melby, J.A.; Rossler, K.J.; Carr, A.V.; Brown, K.A.; Ge, Y. Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics. bioRxiv. 2023.
168. Wancewicz, B.; Zhu, Y.; Fenske, R.K.; Weeks, A.M.; Wenger, K.; Pabich, S.; Daniels, M.; Punt, M.; Nall, R.; Peter, D.C.; Brasier, A.; Cox, E.D.; Davis, D.B.; Ge, Y.; Kimple, M. Metformin Monotherapy Alters the Human Plasma Lipidome Independent of Clinical Markers of Glycemic Control and Cardiovascular Disease Risk in a Type 2 Diabetes Clinical Cohort. J. of Pharmacology and Exp. Therapeutics. 2023. Article
167. Aballo, T. J.; Roberts, D.S.; Bayne, E. F.; Zhu, W.; Walcott, G.; Mahmoud, A. I.; Zhang, J.; Ge, Y. Integrated Proteomics Reveals Alterations in Sarcomere Composition and Developmental Processes during Postnatal Swine Heart Development, J. Mol. Cell. Cardiol. 2023, 176, 33-40 Article
166. Larson, E.J. ; Pergande, M. R; Moss, M. E.; Rossler, K. J.; Wenger, R. K.; Krichel, B.; Josyer, H.; Melby, J. A.; Roberts, D. S.; Pike, K.; Shi, Z.; Chan, H.; Knight, B.; Rogers, H. T.; Brown, K. A.; Ong, I. M.; Kyowon Jeong, K.; Marty, M.; McIlwain, S. J.; Ge, Y. MASH Native: A Unified Solution for Native Top-Down Proteomics Data Processing bioRxiv 2023, doi: 10.1101/2023.01.02.522513 Article
165. Mann, M.; Fu, Y.; Xu, X.; Roberts, D.S.; Li, Y.; Zhou, J., Ge, Y.; Brasier, A.R. Bromodomain-containing Protein 4 Regulates Innate Inflammation in Airway Epithelial Cells via Modulation of Alternative Splicing. bioRxiv. 2023, DOI: 10.1101/2023.01.17.524257 Article
164. Chapman, E.; Aballo, J. J.; Melby, J.A.; Zhou, T.; Price, S. J.; Rossler, K. J.; Lei, I.; Tang, P. C.; Ge, Y. Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-down Proteomics, J. Proteome Res. 2023, 22, 931–941 Article
163. Bayne, E.F.; Rossler, K. J.; Gregorich, Z. R.; Aballo, T. J.; Roberts, D.S.; Chapman, E. A.;Guo, W.; Ralphe, J.C.; Kamp, T.J.; Ge, Y. Top-down Proteomics of Myosin Light Chain Isoforms Define Chamber-Specific Expression in the Human Heart, bioRxiv, 2022. doi: 10.1101/2023.01.26.525767 Article
162. Brown, K. A.; Gugger, M. K.; Roberts, D. S.; Moreno, M.; Chae, P. S.; Ge, Y.; Jin, S. Synthesis, Self-Assembly Properties, and Degradation Characterization of a Nonionic Photocleavable Azo-Sulfide Surfactant Family, Langmuir, 2023, DOI: 10.1021/acs.langmuir.2c02820 Article
161. Wu, Q.; Bell, B.A.; Yan, J.; Chevrette, M.G.; Brittin, N.J.; Zhu, Y.; Chanana, S.; Maity, M.; Braun, D.R.; Wheaton, A.M.; Guzei, I.A.; Ge, Y.; Rajski, S.R.; Thomas, M.G.; Bugni, T.S.; SR Metabolomics and Genomics Enable the Discovery of a New Class of Nonribosomal Peptidic Metallophores from a Marine Micromonospora. J. Am. Chem. Soc. 2023, 145, 58–69. Article
160. Brown, K.A.; Gugger, M.; Yu, Z.; Moreno, D.; Jin, S.; Ge, Y. A Nonionic, Cleavable Surfactant for Native Mass Spectrometry and Top-down Proteomics, Anal. Chem. 2023, 95, 1801–1804 Article
159. Wu, Q.; Bell, B.A.; Yan, J.; Chevrette, M.G.; Brittin, N.J.; Zhu, Y.; Chanana, S.; Maity, M.; Braun, D.R.; Wheaton, A.M.; Guzei, I.A.; Ge, Y.; Rajski, S.R.; Thomas, M.G.; Bugni, T.S.; SR Metabolomics and Genomics Enable the Discovery of a New Class of Nonribosomal Peptidic Metallophores from a Marine Micromonospora. J. Am. Chem. Soc., 2022, Online ahead of print. Article
158.  Sun M.; Jin Y.; Zhang Y.; Gregorich Z.R.; Ren J.; Ge Y.; Guo W.; SR Protein Kinases Regulate the Splicing of Cardiomyopathy-Relevant Genes via Phosphorylation of the RSRSP Stretch in RBM20. Genes, 2022, 13(9), 1526. Article.
157.  Roberts, D.S.; Mann, M.; Li, B.H.; Kim, D.; Brasier, A.R.; Jin, S. Ge, Y. Distinct Core Glycan and O-Glycoform Utilization of SARS-CoV-2 Omicron Variant Spike Protein RBD Revealed by Top-Down Mass Spectrometry. Chem. Sci. 2022, Epub ahead of print. Article.
156.  Larson, E.J.; Gregorich, Z.R.; Zhang, Y.; Li, B.H.; Aballo, T.J.; Melby, J.A.; Ge, Y.; Guo, W. RBM20 Ablation is Associated With Changes in The Expression of Titin-Interacting and Metabolic Proteins. Molecular Omics, 2022. Article.
155. Gupta, K.; Brown, K.A.; Hsieh, M.L.; Hoover, B.; Wang, J.; Khoury, M.K.; Pilli, V.S.S.; Beyer, R.S.; Voruganti, N.R.; Chaudhary, S.; Roberts, D.S.; Murphy, R.M.; Hong, S.; Ge, Y.; Liu, B. Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL. Journal of Extracellular Vesicles, 2022, 11, e12261. Article.
154. Zhu, Y.; Esnault, S.; Ge, Y.; Jarjour, N.N; Brasier, A.R. Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling. Clin Proteomics. 2022, 19(1), 15. Article.
153. Zhu, Y.; Esnault, S.; Ge, Y.; Jarjour, N.N.; Brasier, A.R. Segmental Bronchial Allergen Challenge Elicits Distinct Metabolic Phenotypes in Allergic Asthma. Metabolites, 2022, 12(5), 381. Article.
152. Tiambeng, T.N.; Wu, Z.; Melby, J.A.; Ge, Y. Size Exclusion Chromatography Strategies and MASH Explorer for Large Proteoform Characterization. Methods Mol Biol. 2022, 2500, 15-30. Article.
151. Zhang, Y.; Wang, C.; Sun, M.; Jin, Y.; Braz, C.U.; Khatib, H.; Hacker, T.A.; Liss, M.; Gotthardt, M.; Granzier, H.; Ge, Y.; Guo, W. RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis. FASEB Journal, 2022, Epub ahead of print. Article.
150. Buck, K.M.; Roberts, D.S.; Aballo, T.J.; Inman, D.R.; Jin, S.; Ponik, S.; Brown, K.A.; Ge, Y. One-Pot Exosome Proteomics Enabled by a Photocleavable Surfactant. Anal. Chem., 2022, 94, 7164-7168. Article.
149. Li, A.; Campbell, K.; Lal, S.; Ge, Y.; Keogh, A.; Macdonald, P.S.; Lau, P.; Linke, W.A.; Van der Velden, J.; Field, A.; Martinac, B.; Grosser, M.; dos Remedios, C. Peripartum cardiomyopathy: a global effort to find the cause and cure for the rare and little understood disease Biophysical Reviews. 2022, 14, 369-379. Article.

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